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Triazole RGD antagonist reverts TGFβ1-induced endothelial-to-mesenchymal transition in endothelial precursor cells
Fibrosis is the dramatic consequence of a dysregulated reparative process in which activated fibroblasts (myofibroblasts) and Transforming Growth Factor β1 (TGFβ1) play a central role. When exposed to TGFβ1, fibroblast and epithelial cells differentiate in myofibroblasts; in addition, endothelial ce...
Autores principales: | Bianchini, Francesca, Peppicelli, Silvia, Fabbrizzi, Pierangelo, Biagioni, Alessio, Mazzanti, Benedetta, Menchi, Gloria, Calorini, Lido, Pupi, Alberto, Trabocchi, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219041/ https://www.ncbi.nlm.nih.gov/pubmed/27761847 http://dx.doi.org/10.1007/s11010-016-2847-2 |
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