Cargando…

Predicted neoantigen load in non-hypermutated endometrial cancers: Correlation with outcome and tumor-specific genomic alterations

Elevated neoantigen load has been previously correlated with improved outcome and response to immune checkpoint blockade in various tumor types. In endometrial cancer, previous studies of neoantigen load prediction have shown that the hypermutated MSI and POLE-mutated tumors harbor significantly hig...

Descripción completa

Detalles Bibliográficos
Autores principales: Shukla, Sachet A., Howitt, Brooke E., Wu, Catherine J., Konstantinopoulos, Panagiotis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219603/
https://www.ncbi.nlm.nih.gov/pubmed/28070553
http://dx.doi.org/10.1016/j.gore.2016.12.009