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Differential long-term stability of microRNAs and RNU6B snRNA in 12–20 year old archived formalin-fixed paraffin-embedded specimens

BACKGROUND: The quantitative analysis of microRNA (miRNA) gene expression in archived formalin-fixed, paraffin embedded (FFPE) tissues has been instrumental to identifying their potential roles in cancer biology, diagnosis, and prognosis. However, it remains unclear whether miRNAs remain stable in F...

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Detalles Bibliográficos
Autores principales: Peskoe, Sarah B., Barber, John R., Zheng, Qizhi, Meeker, Alan K., De Marzo, Angelo M., Platz, Elizabeth A., Lupold, Shawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219687/
https://www.ncbi.nlm.nih.gov/pubmed/28061773
http://dx.doi.org/10.1186/s12885-016-3008-4