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CX(3)C chemokine receptor 1 deficiency modulates microglia morphology but does not affect lesion size and short-term deficits after experimental stroke

BACKGROUND: The fractalkine/CX(3)C chemokine receptor 1 (CX(3)CR1) pathway has been identified to play an essential role in the chemotaxis of microglia, leukocyte trafficking and microglia/macrophage recruitment. It has also been shown to be important in the regulation of the inflammatory response i...

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Detalles Bibliográficos
Autores principales: van der Maten, Gerlinde, Henck, Vivien, Wieloch, Tadeusz, Ruscher, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219711/
https://www.ncbi.nlm.nih.gov/pubmed/28061814
http://dx.doi.org/10.1186/s12868-016-0325-0