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Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

Osteosarcoma is the most common primary bone cancer affecting children and adolescents worldwide. Despite an incidence of three cases per million annually, it accounts for an inordinate amount of morbidity and mortality. While the use of chemotherapy (cisplatin, doxorubicin, and methotrexate) in the...

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Detalles Bibliográficos
Autores principales: Angulo, Pablo, Kaushik, Gaurav, Subramaniam, Dharmalingam, Dandawate, Prasad, Neville, Kathleen, Chastain, Katherine, Anant, Shrikant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219787/
https://www.ncbi.nlm.nih.gov/pubmed/28061797
http://dx.doi.org/10.1186/s13045-016-0373-z