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From Stock Bottle to Vaccine: Elucidating the Particle Size Distributions of Aluminum Adjuvants Using Dynamic Light Scattering

The physicochemical properties of aluminum salts are key determinants of their resultant adjuvanticity in vivo when administered as part of a vaccine. While there are links between particle size and the efficacy of the immune response, the limited literature directly characterizing the PSD of alumin...

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Detalles Bibliográficos
Autores principales: Shardlow, Emma, Mold, Matthew, Exley, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220009/
https://www.ncbi.nlm.nih.gov/pubmed/28119911
http://dx.doi.org/10.3389/fchem.2016.00048