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GATA1 Activity Governed by Configurations of cis-Acting Elements

The transcription factor GATA1 regulates the expression of essential erythroid and megakaryocytic differentiation genes through binding to the DNA consensus sequence WGATAR. The GATA1 protein has four functional domains, including two centrally located zinc-finger domains and two transactivation dom...

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Detalles Bibliográficos
Autores principales: Hasegawa, Atsushi, Shimizu, Ritsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220053/
https://www.ncbi.nlm.nih.gov/pubmed/28119852
http://dx.doi.org/10.3389/fonc.2016.00269