In silico Approach for Anti-Thrombosis Drug Discovery: P2Y(1)R Structure-Based TCMs Screening

Cardiovascular diseases (CVDs), including thrombosis, which is induced by platelet aggregation, are the leading cause of mortality worldwide. The P2Y(1) receptor (P2Y(1)R) facilitates platelet aggregation and is thus an important potential anti-thrombotic drug target. The P2Y(1)R protein structure c...

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Detalles Bibliográficos
Autores principales: Yi, Fan, Sun, Le, Xu, Li-jia, Peng, Yong, Liu, Hai-bo, He, Chun-nian, Xiao, Pei-gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220089/
https://www.ncbi.nlm.nih.gov/pubmed/28119608
http://dx.doi.org/10.3389/fphar.2016.00531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220089/
https://www.ncbi.nlm.nih.gov/pubmed/28119608
http://dx.doi.org/10.3389/fphar.2016.00531

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