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Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching

BACKGROUND: Tumour budding, described as the presence of single cells or small clusters of up to five tumour cells at the invasive margin, is established as a prognostic marker in colorectal carcinoma. In the present study, we aimed to investigate the molecular signature of tumour budding cells and...

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Detalles Bibliográficos
Autores principales: De Smedt, Linde, Palmans, Sofie, Andel, Daan, Govaere, Olivier, Boeckx, Bram, Smeets, Dominiek, Galle, Eva, Wouters, Jasper, Barras, David, Suffiotti, Madeleine, Dekervel, Jeroen, Tousseyn, Thomas, De Hertogh, Gert, Prenen, Hans, Tejpar, Sabine, Lambrechts, Diether, Sagaert, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220148/
https://www.ncbi.nlm.nih.gov/pubmed/27884016
http://dx.doi.org/10.1038/bjc.2016.382