Methyl-CpG-binding domain 3 inhibits epithelial–mesenchymal transition in pancreatic cancer cells via TGF-β/Smad signalling

BACKGROUND: Methyl-CpG-binding domain 3 (MBD3) is an aberrant expression in human malignancies. However, the role of MBD3 in pancreatic cancer progression remains to be clarified. In this study, we investigated the effects of MBD3 on the epithelial–mesenchymal transition (EMT), and the underlying me...

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Detalles Bibliográficos
Autores principales: Xu, Min, He, Junbo, Li, Jie, Feng, Wen, Zhou, Hailang, Wei, Hong, Zhou, Meng, Lu, Ying, Zeng, Jian, Peng, Wanxin, Du, Fengyi, Gong, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220156/
https://www.ncbi.nlm.nih.gov/pubmed/27898661
http://dx.doi.org/10.1038/bjc.2016.397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220156/
https://www.ncbi.nlm.nih.gov/pubmed/27898661
http://dx.doi.org/10.1038/bjc.2016.397

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