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Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes

BACKGROUND/OBJECTIVES: Myostatin (Mstn) has a pivotal role in glucose and lipid metabolism. Mstn deficiency leads to the increased browning of white adipose tissue (WAT), which results in the increased energy expenditure and protection against diet-induced obesity and insulin resistance. In this stu...

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Detalles Bibliográficos
Autores principales: Ge, X, Sathiakumar, D, Lua, B J G, Kukreti, H, Lee, M, McFarlane, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220162/
https://www.ncbi.nlm.nih.gov/pubmed/27297797
http://dx.doi.org/10.1038/ijo.2016.110