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Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes
BACKGROUND/OBJECTIVES: Myostatin (Mstn) has a pivotal role in glucose and lipid metabolism. Mstn deficiency leads to the increased browning of white adipose tissue (WAT), which results in the increased energy expenditure and protection against diet-induced obesity and insulin resistance. In this stu...
Autores principales: | Ge, X, Sathiakumar, D, Lua, B J G, Kukreti, H, Lee, M, McFarlane, C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220162/ https://www.ncbi.nlm.nih.gov/pubmed/27297797 http://dx.doi.org/10.1038/ijo.2016.110 |
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