Inhibition of Akt phosphorylation attenuates resistance to TNF-α cytotoxic effects in MCF-7 cells, but not in their doxorubicin resistant derivatives

OBJECTIVE(S): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of TNF-α. In this study, we investigated the role...

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Detalles Bibliográficos
Autores principales: Ghandadi, Morteza, Mohammadi, Atieh, Behravan, Javad, Abnous, Khalil, Haj-Ali, Negin, Gharaee, Melika Ehtesham, Mosaffa, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220243/
https://www.ncbi.nlm.nih.gov/pubmed/28096970
http://dx.doi.org/10.22038/ijbms.2016.7924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220243/
https://www.ncbi.nlm.nih.gov/pubmed/28096970
http://dx.doi.org/10.22038/ijbms.2016.7924

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