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Inhibition of Akt phosphorylation attenuates resistance to TNF-α cytotoxic effects in MCF-7 cells, but not in their doxorubicin resistant derivatives

OBJECTIVE(S): Acquisition of TNF-α resistance plays role in the onset and growth of malignant tumors. Previous studies have demonstrated that MCF-7 cell line and its doxorubicin resistant variant MCF-7/Adr are resistant against the cytotoxic effects of TNF-α. In this study, we investigated the role...

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Detalles Bibliográficos
Autores principales:	Ghandadi, Morteza, Mohammadi, Atieh, Behravan, Javad, Abnous, Khalil, Haj-Ali, Negin, Gharaee, Melika Ehtesham, Mosaffa, Fatemeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220243/ https://www.ncbi.nlm.nih.gov/pubmed/28096970 http://dx.doi.org/10.22038/ijbms.2016.7924

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