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Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue

OBJECTIVE: Insulin signaling plays a unique role in the regulation of energy homeostasis and the impairment of insulin action is associated with altered lipid metabolism, obesity, and Type 2 Diabetes. The main aim of this study was to provide further insight into the regulatory mechanisms governing...

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Detalles Bibliográficos
Autores principales: Cederquist, Carly T., Lentucci, Claudia, Martinez-Calejman, Camila, Hayashi, Vanessa, Orofino, Joseph, Guertin, David, Fried, Susan K., Lee, Mi-Jeong, Cardamone, M. Dafne, Perissi, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220281/
https://www.ncbi.nlm.nih.gov/pubmed/28123943
http://dx.doi.org/10.1016/j.molmet.2016.10.007