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Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers
Recent studies found that membrane-bound K-Ras dimers are important for biological function. However, the structure and thermodynamic stability of these complexes remained unknown because they are hard to probe by conventional approaches. Combining data from a wide range of computational and experim...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220301/ https://www.ncbi.nlm.nih.gov/pubmed/28067274 http://dx.doi.org/10.1038/srep40109 |