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Chimeric virus-like particles containing influenza HA antigen and GPI-CCL28 induce long-lasting mucosal immunity against H3N2 viruses

Influenza virus is a significant cause of morbidity and mortality, with worldwide seasonal epidemics. The duration and quality of humoral immunity and generation of immunological memory to vaccines is critical for protective immunity. In the current study, we examined the long-lasting protective eff...

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Detalles Bibliográficos
Autores principales: Mohan, Teena, Berman, Zachary, Luo, Yuan, Wang, Chao, Wang, Shelly, Compans, Richard W., Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220311/
https://www.ncbi.nlm.nih.gov/pubmed/28067290
http://dx.doi.org/10.1038/srep40226