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SDF-1/CXCR4 axis induces human dental pulp stem cell migration through FAK/PI3K/Akt and GSK3β/β-catenin pathways

SDF-1 (stromal cell derived factor-1) has been found to be widely expressed during dental pulp inflammation, while hDPSCs (human dental pulp stem cells) contribute to the repair of dental pulp. We showed that the migration of hDPSCs was induced by SDF-1 in a concentration-dependent manner and could...

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Detalles Bibliográficos
Autores principales: Li, Mingwei, Sun, Xuefei, Ma, Liang, Jin, Lu, Zhang, Wenfei, Xiao, Min, Yu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220312/
https://www.ncbi.nlm.nih.gov/pubmed/28067275
http://dx.doi.org/10.1038/srep40161