Two-Step Amyloid Aggregation: Sequential Lag Phase Intermediates

The self-assembly of proteins into fibrillar structures called amyloid fibrils underlies the onset and symptoms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. However, the molecular basis and mechanism of amyloid aggregation are not completely understood. For many amyloidogenic...

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Detalles Bibliográficos
Autores principales: Castello, Fabio, Paredes, Jose M., Ruedas-Rama, Maria J., Martin, Miguel, Roldan, Mar, Casares, Salvador, Orte, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220338/
https://www.ncbi.nlm.nih.gov/pubmed/28067252
http://dx.doi.org/10.1038/srep40065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220338/
https://www.ncbi.nlm.nih.gov/pubmed/28067252
http://dx.doi.org/10.1038/srep40065

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