Sec16A is critical for both conventional and unconventional secretion of CFTR

CFTR is a transmembrane protein that reaches the cell surface via the conventional Golgi mediated secretion pathway. Interestingly, ER-to-Golgi blockade or ER stress induces alternative GRASP-mediated, Golgi-bypassing unconventional trafficking of wild-type CFTR and the disease-causing ΔF508-CFTR, w...

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Detalles Bibliográficos
Autores principales: Piao, He, Kim, Jiyoon, Noh, Shin Hye, Kweon, Hee-Seok, Kim, Joo Young, Lee, Min Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220342/
https://www.ncbi.nlm.nih.gov/pubmed/28067262
http://dx.doi.org/10.1038/srep39887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220342/
https://www.ncbi.nlm.nih.gov/pubmed/28067262
http://dx.doi.org/10.1038/srep39887

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