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Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1

OBJECTIVE: Celastrol was recently identified as a potential novel treatment for obesity. However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive. The aim of this study is to evaluate the role of Celastrol in NAFLD. METHODS: Functional studies were performed using...

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Detalles Bibliográficos
Autores principales: Zhang, Yinliang, Geng, Chao, Liu, Xiaoyan, Li, Meixia, Gao, Mingyue, Liu, Xiaojun, Fang, Fude, Chang, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220393/
https://www.ncbi.nlm.nih.gov/pubmed/28123944
http://dx.doi.org/10.1016/j.molmet.2016.11.002