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A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism
OBJECTIVE: Increased fructose consumption is a contributor to the burgeoning epidemic of non-alcoholic fatty liver disease (NAFLD). Recent evidence indicates that the metabolic hormone FGF21 is regulated by fructose consumption in humans and rodents and may play a functional role in this nutritional...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220398/ https://www.ncbi.nlm.nih.gov/pubmed/28123933 http://dx.doi.org/10.1016/j.molmet.2016.11.008 |