Identification of a Novel ENU-Induced Mutation in Mouse Tbx1 Linked to Human DiGeorge Syndrome

The patients with DiGeorge syndrome (DGS), caused by deletion containing dozens of genes in chromosome 22, often carry cardiovascular problem and hearing loss associated with chronic otitis media. Inside the deletion region, a transcription factor TBX1 was highly suspected. Furthermore, similar DGS...

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Detalles Bibliográficos
Autores principales: Chen, Jiaofeng, Zhang, Xue, Li, Jie, Song, Chenmeng, Jia, Yichang, Xiong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220494/
https://www.ncbi.nlm.nih.gov/pubmed/28105375
http://dx.doi.org/10.1155/2016/5836143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220494/
https://www.ncbi.nlm.nih.gov/pubmed/28105375
http://dx.doi.org/10.1155/2016/5836143

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