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Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases

The ubiquitin-proteasome pathway (UPP) is a hallmark of the eukaryotic cell. In jawed vertebrates, it has been co-opted by the adaptive immune system, where proteasomal degradation produces endogenous peptides for major histocompatibility complex class I antigen presentation. However, proteolytic pr...

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Detalles Bibliográficos
Autores principales: Candido-Ferreira, Ivan Lavander, Kronenberger, Thales, Sayegh, Raphael Santa Rosa, Batista, Isabel de Fátima Correia, da Silva Junior, Pedro Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220581/
https://www.ncbi.nlm.nih.gov/pubmed/28119686
http://dx.doi.org/10.3389/fimmu.2016.00664