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Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases
The ubiquitin-proteasome pathway (UPP) is a hallmark of the eukaryotic cell. In jawed vertebrates, it has been co-opted by the adaptive immune system, where proteasomal degradation produces endogenous peptides for major histocompatibility complex class I antigen presentation. However, proteolytic pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220581/ https://www.ncbi.nlm.nih.gov/pubmed/28119686 http://dx.doi.org/10.3389/fimmu.2016.00664 |