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Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1(+) monocytes

AIMS: Atherosclerosis is a chronic inflammatory disease occurring within the artery wall. A crucial step in atherogenesis is the infiltration and retention of monocytes into the subendothelial space of large arteries induced by chemokines and growth factors. Angiopoietin-1 (Ang-1) regulates angiogen...

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Detalles Bibliográficos
Autores principales: Fujisawa, Takeshi, Wang, Keqing, Niu, Xi-Lin, Egginton, Stuart, Ahmad, Shakil, Hewett, Peter, Kontos, Christopher D., Ahmed, Asif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220674/
https://www.ncbi.nlm.nih.gov/pubmed/28069704
http://dx.doi.org/10.1093/cvr/cvw223