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Iterative error correction of long sequencing reads maximizes accuracy and improves contig assembly

Next-generation sequencers such as Illumina can now produce reads up to 300 bp with high throughput, which is attractive for genome assembly. A first step in genome assembly is to computationally correct sequencing errors. However, correcting all errors in these longer reads is challenging. Here, we...

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Detalles Bibliográficos
Autores principales: Sameith, Katrin, Roscito, Juliana G, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221426/
https://www.ncbi.nlm.nih.gov/pubmed/26868358
http://dx.doi.org/10.1093/bib/bbw003