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Iterative error correction of long sequencing reads maximizes accuracy and improves contig assembly
Next-generation sequencers such as Illumina can now produce reads up to 300 bp with high throughput, which is attractive for genome assembly. A first step in genome assembly is to computationally correct sequencing errors. However, correcting all errors in these longer reads is challenging. Here, we...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221426/ https://www.ncbi.nlm.nih.gov/pubmed/26868358 http://dx.doi.org/10.1093/bib/bbw003 |