Interaction with adenylate cyclase toxin from Bordetella pertussis affects the metal binding properties of calmodulin

Adenylate cyclase toxin domain (CyaA‐ACD) is a calmodulin (CaM)‐dependent adenylate cyclase involved in Bordetella pertussis pathogenesis. Calcium (Ca(2+)) and magnesium (Mg(2+)) concentrations impact CaM‐dependent CyaA‐ACD activation, but the structural mechanisms remain unclear. In this study, NMR...

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Detalles Bibliográficos
Autores principales: Springer, Tzvia I., Emerson, Corey C., Johns, Christian W., Finley, Natosha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221433/
https://www.ncbi.nlm.nih.gov/pubmed/28097085
http://dx.doi.org/10.1002/2211-5463.12138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221433/
https://www.ncbi.nlm.nih.gov/pubmed/28097085
http://dx.doi.org/10.1002/2211-5463.12138

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