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Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin

The skin is an ideal target tissue for vaccine delivery for a number of reasons. It is highly accessible, and most importantly, enriched in professional antigen presenting cells. Possessing strong similarities to human skin physiology and displaying a defined epidermis, the guinea pig is an appropri...

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Detalles Bibliográficos
Autores principales: Schultheis, Katherine, Schaefer, Hubert, Yung, Bryan S., Oh, Janet, Muthumani, Karuppiah, Humeau, Laurent, Broderick, Kate E., Smith, Trevor R.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221502/
https://www.ncbi.nlm.nih.gov/pubmed/27894716
http://dx.doi.org/10.1016/j.vaccine.2016.11.052