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Heterogeneous architecture of vertebrate kinetochores revealed by three-dimensional superresolution fluorescence microscopy

The kinetochore is often depicted as having a disk-like architecture in which the outer layer of proteins, which engage microtubules and control checkpoint signaling, are built on a static inner layer directly linked to CENP-A chromatin. Here, applying three-dimensional (3D) structural illumination...

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Detalles Bibliográficos
Autores principales: Wynne, David J., Funabiki, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221576/
https://www.ncbi.nlm.nih.gov/pubmed/27170176
http://dx.doi.org/10.1091/mbc.E16-02-0130