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Effects of anchor structure and glycosylation of Fcγ receptor III on ligand binding affinity

Isoforms of the Fcγ receptor III (FcγRIII or CD16) are cell surface receptors for the Fc portion of IgG and important regulators of humoral immune responses. Different ligand binding kinetics of FcγRIII isoforms are obtained in three dimensions by surface plasmon resonance and in two dimensions by a...

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Detalles Bibliográficos
Autores principales: Jiang, Ning, Chen, Wei, Jothikumar, Prithiviraj, Patel, Jaina M., Shashidharamurthy, Rangaiah, Selvaraj, Periasamy, Zhu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221579/
https://www.ncbi.nlm.nih.gov/pubmed/27582391
http://dx.doi.org/10.1091/mbc.E16-06-0470