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Loss of G(α12/13) exacerbates apical area dependence of actomyosin contractility

During development, coordinated cell shape changes alter tissue shape. In the Drosophila ventral furrow and other epithelia, apical constriction of hundreds of epithelial cells folds the tissue. Genes in the G(α12/13) pathway coordinate collective apical constriction, but the mechanism of coordinati...

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Detalles Bibliográficos
Autores principales: Xie, Shicong, Mason, Frank M., Martin, Adam C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221585/
https://www.ncbi.nlm.nih.gov/pubmed/27489340
http://dx.doi.org/10.1091/mbc.E16-05-0305