Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling

The allergic response is initiated on the plasma membrane of mast cells by phosphorylation of the receptor for immunoglobulin E (IgE), FcεRI, by Lyn kinase after IgE-FcεRI complexes are cross-linked by multivalent antigen. Signal transduction requires reorganization of receptors and membrane signali...

Descripción completa

Detalles Bibliográficos
Autores principales: Shelby, Sarah A., Veatch, Sarah L., Holowka, David A., Baird, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221596/
https://www.ncbi.nlm.nih.gov/pubmed/27682583
http://dx.doi.org/10.1091/mbc.E16-06-0425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221596/
https://www.ncbi.nlm.nih.gov/pubmed/27682583
http://dx.doi.org/10.1091/mbc.E16-06-0425

Ejemplares similares