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Functional nanoscale coupling of Lyn kinase with IgE-FcεRI is restricted by the actin cytoskeleton in early antigen-stimulated signaling

The allergic response is initiated on the plasma membrane of mast cells by phosphorylation of the receptor for immunoglobulin E (IgE), FcεRI, by Lyn kinase after IgE-FcεRI complexes are cross-linked by multivalent antigen. Signal transduction requires reorganization of receptors and membrane signali...

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Detalles Bibliográficos
Autores principales:	Shelby, Sarah A., Veatch, Sarah L., Holowka, David A., Baird, Barbara A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221596/ https://www.ncbi.nlm.nih.gov/pubmed/27682583 http://dx.doi.org/10.1091/mbc.E16-06-0425

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