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Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord blood

Cord blood is widely used as surrogate tissue in epigenome-wide association studies of prenatal conditions. Cell type composition variation across samples can be an important confounder of epigenome-wide association studies in blood that constitute a mixture of cells. We evaluated a newly developed...

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Detalles Bibliográficos
Autores principales: Cardenas, Andres, Allard, Catherine, Doyon, Myriam, Houseman, E. Andres, Bakulski, Kelly M., Perron, Patrice, Bouchard, Luigi, Hivert, Marie-France
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221601/
https://www.ncbi.nlm.nih.gov/pubmed/27668573
http://dx.doi.org/10.1080/15592294.2016.1233091