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Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA

Linker of Nucleoskeleton and Cytoskeleton (LINC) complexes span the nuclear envelope and transduce force from dynamic cytoskeletal networks to the nuclear lamina. Here we show that LINC complexes also signal from the nuclear envelope to critical regulators of the actin cytoskeleton. Specifically, we...

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Detalles Bibliográficos
Autores principales: Thakar, Ketan, May, Christopher K., Rogers, Anna, Carroll, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221622/
https://www.ncbi.nlm.nih.gov/pubmed/28035049
http://dx.doi.org/10.1091/mbc.E16-06-0467