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Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics
Mitotic motor proteins generate force to establish and maintain spindle bipolarity, but how they are temporally and spatially regulated in vivo is unclear. Prior work demonstrated that a microtubule-associated protein, TPX2, targets kinesin-5 and kinesin-12 motors to spindle microtubules. The C-term...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221630/ https://www.ncbi.nlm.nih.gov/pubmed/27852894 http://dx.doi.org/10.1091/mbc.E16-06-0476 |