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Replacing 5-fluorouracil by capecitabine in localised squamous cell carcinoma of the anal canal: systematic review and meta-analysis

BACKGROUND: The standard treatment for localised squamous cell carcinoma of the anal canal (SCCAC) is chemoradiotherapy (CRT) with infusional 5-fluorouracil (5-FU) and mitomycin. Because 5-FU and capecitabine have offered similar efficacy in many phase-III trials of solid tumours, studies have teste...

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Detalles Bibliográficos
Autores principales: Souza, Karla T, Pereira, Allan AL, Araujo, Raphael L, Oliveira, Suilane Coelho Ribeiro, Hoff, Paulo M, Riechelmann, Rachel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221636/
https://www.ncbi.nlm.nih.gov/pubmed/28105070
http://dx.doi.org/10.3332/ecancer.2016.699