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Balance between sodium and calcium currents underlying chronic atrial fibrillation termination: An in silico intersubject variability study

BACKGROUND: Atrial remodeling as a result of long-standing persistent atrial fibrillation (AF) induces substrate modifications that lead to different perpetuation mechanisms than in paroxysmal AF and a reduction in the efficacy of antiarrhythmic treatments. OBJECTIVE: The purpose of this study was t...

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Detalles Bibliográficos
Autores principales: Liberos, Alejandro, Bueno-Orovio, Alfonso, Rodrigo, Miguel, Ravens, Ursula, Hernandez-Romero, Ismael, Fernandez-Aviles, Francisco, Guillem, Maria S., Rodriguez, Blanca, Climent, Andreu M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221730/
https://www.ncbi.nlm.nih.gov/pubmed/27569443
http://dx.doi.org/10.1016/j.hrthm.2016.08.028