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Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway
Keratinocyte migration, the initial event and rate-limiting step in wound healing, plays a vital role in restoration of the intact skin barrier, also known as re-epithelialization. After acute tissue injury, hypoxic microenvironment gradually develops and acts as an early stimulus to initiate the he...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221764/ https://www.ncbi.nlm.nih.gov/pubmed/28068384 http://dx.doi.org/10.1371/journal.pone.0169155 |