Simultaneous delivery of anti-miR21 with doxorubicin prodrug by mimetic lipoprotein nanoparticles for synergistic effect against drug resistance in cancer cells

The development of drug resistance in cancer cells is one of the major obstacles to achieving effective chemotherapy. We hypothesized that the combination of a doxorubicin (Dox) prodrug and microRNA (miR)21 inhibitor might show synergistic antitumor effects on drug-resistant breast cancer cells. In...

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Detalles Bibliográficos
Autores principales: Rui, Mengjie, Qu, Yang, Gao, Tong, Ge, Yanru, Feng, Chunlai, Xu, Ximing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221799/
https://www.ncbi.nlm.nih.gov/pubmed/28115844
http://dx.doi.org/10.2147/IJN.S122171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221799/
https://www.ncbi.nlm.nih.gov/pubmed/28115844
http://dx.doi.org/10.2147/IJN.S122171

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