Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization

The broadest clinical application of siRNA therapeutics will be facilitated by drug-loaded delivery systems that maintain stability and potency for long times under ambient conditions. In the present study, we seek to better understand the stability and effect of storage conditions on lipidoid nanop...

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Detalles Bibliográficos
Autores principales: Ball, Rebecca L, Bajaj, Palak, Whitehead, Kathryn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221800/
https://www.ncbi.nlm.nih.gov/pubmed/28115848
http://dx.doi.org/10.2147/IJN.S123062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221800/
https://www.ncbi.nlm.nih.gov/pubmed/28115848
http://dx.doi.org/10.2147/IJN.S123062

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