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Achieving long-term stability of lipid nanoparticles: examining the effect of pH, temperature, and lyophilization
The broadest clinical application of siRNA therapeutics will be facilitated by drug-loaded delivery systems that maintain stability and potency for long times under ambient conditions. In the present study, we seek to better understand the stability and effect of storage conditions on lipidoid nanop...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221800/ https://www.ncbi.nlm.nih.gov/pubmed/28115848 http://dx.doi.org/10.2147/IJN.S123062 |