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Reprogramming Malignant Cancer Cells toward a Benign Phenotype following Exposure to Human Embryonic Stem Cell Microenvironment

The embryonic microenvironment is well known to be non-permissive for tumor development because early developmental signals naturally suppress the expression of proto-oncogenes. In an analogous manner, mimicking an early embryonic environment during embryonic stem cell culture has been shown to supp...

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Detalles Bibliográficos
Autores principales: Zhou, Shufeng, Abdouh, Mohamed, Arena, Vincenzo, Arena, Manuel, Arena, Goffredo Orazio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222525/
https://www.ncbi.nlm.nih.gov/pubmed/28068409
http://dx.doi.org/10.1371/journal.pone.0169899