Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

The causative agent of toxoplasmosis, the intracellular parasite Toxoplasma gondii, delivers a protein, GRA24, into the cells it infects that interacts with the mitogen-activated protein (MAP) kinase p38α (MAPK14), leading to activation and nuclear translocation of the host kinase and a subsequent i...

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Detalles Bibliográficos
Autores principales: Pellegrini, Erika, Palencia, Andrés, Braun, Laurence, Kapp, Ulrike, Bougdour, Alexandre, Belrhali, Hassan, Bowler, Matthew W., Hakimi, Mohamed-Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222587/
https://www.ncbi.nlm.nih.gov/pubmed/27889209
http://dx.doi.org/10.1016/j.str.2016.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222587/
https://www.ncbi.nlm.nih.gov/pubmed/27889209
http://dx.doi.org/10.1016/j.str.2016.10.011

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