Normalisation against Circadian and Age-Related Disturbances Enables Robust Detection of Gene Expression Changes in Liver of Aged Mice

The expression of some genes is affected by age. To detect such age-related changes, their expression levels are related to constant marker genes. However, transcriptional noise increasing with advancing age renders difficult the identification of real age-related changes because it may affect the m...

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Detalles Bibliográficos
Autores principales: Fonseca Costa, Sara S., Wegmann, Daniel, Ripperger, Jürgen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222604/
https://www.ncbi.nlm.nih.gov/pubmed/28068403
http://dx.doi.org/10.1371/journal.pone.0169615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222604/
https://www.ncbi.nlm.nih.gov/pubmed/28068403
http://dx.doi.org/10.1371/journal.pone.0169615

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