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In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-coding RNA Pathways

Understanding RNA processing and turnover requires knowledge of cleavages by major endoribonucleases within a living cell. We have employed TIER-seq (transiently inactivating an endoribonuclease followed by RNA-seq) to profile cleavage products of the essential endoribonuclease RNase E in Salmonella...

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Detalles Bibliográficos
Autores principales: Chao, Yanjie, Li, Lei, Girodat, Dylan, Förstner, Konrad U., Said, Nelly, Corcoran, Colin, Śmiga, Michał, Papenfort, Kai, Reinhardt, Richard, Wieden, Hans-Joachim, Luisi, Ben F., Vogel, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222698/
https://www.ncbi.nlm.nih.gov/pubmed/28061332
http://dx.doi.org/10.1016/j.molcel.2016.11.002