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XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development
Sex chromosome dosage compensation is essential in most metazoans, but the developmental timing and underlying mechanisms vary significantly, even among placental mammals. Here we identify human-specific mechanisms regulating X chromosome activity in early embryonic development. Single-cell RNA sequ...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222720/ https://www.ncbi.nlm.nih.gov/pubmed/27989768 http://dx.doi.org/10.1016/j.stem.2016.10.014 |