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XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development

Sex chromosome dosage compensation is essential in most metazoans, but the developmental timing and underlying mechanisms vary significantly, even among placental mammals. Here we identify human-specific mechanisms regulating X chromosome activity in early embryonic development. Single-cell RNA sequ...

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Detalles Bibliográficos
Autores principales:	Vallot, Céline, Patrat, Catherine, Collier, Amanda J., Huret, Christophe, Casanova, Miguel, Liyakat Ali, Tharvesh M., Tosolini, Matteo, Frydman, Nelly, Heard, Edith, Rugg-Gunn, Peter J., Rougeulle, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Short Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222720/ https://www.ncbi.nlm.nih.gov/pubmed/27989768 http://dx.doi.org/10.1016/j.stem.2016.10.014

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