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Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs

Numerous long intervening noncoding RNAs (lincRNAs) are generated from the mammalian genome by RNA polymerase II (Pol II) transcription. Although multiple functions have been ascribed to lincRNAs, their synthesis and turnover remain poorly characterized. Here, we define systematic differences in tra...

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Detalles Bibliográficos
Autores principales: Schlackow, Margarita, Nojima, Takayuki, Gomes, Tomas, Dhir, Ashish, Carmo-Fonseca, Maria, Proudfoot, Nick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222723/
https://www.ncbi.nlm.nih.gov/pubmed/28017589
http://dx.doi.org/10.1016/j.molcel.2016.11.029