Fractalkine Signaling Attenuates Perivascular Clustering of Microglia and Fibrinogen Leakage during Systemic Inflammation in Mouse Models of Diabetic Retinopathy

Fractalkine (FKN) is a chemokine expressed constitutively by healthy neurons and signals to microglia upon interaction with the FKN receptor, CX3CR1. Signaling between FKN and CX3CR1 transduces inhibitory signals that ameliorate microglial activation and proinflammatory cytokine release in neuroinfl...

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Detalles Bibliográficos
Autores principales: Mendiola, Andrew S., Garza, Rolando, Cardona, Sandra M., Mythen, Shannon A., Lira, Sergio A., Akassoglou, Katerina, Cardona, Astrid E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222852/
https://www.ncbi.nlm.nih.gov/pubmed/28119571
http://dx.doi.org/10.3389/fncel.2016.00303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222852/
https://www.ncbi.nlm.nih.gov/pubmed/28119571
http://dx.doi.org/10.3389/fncel.2016.00303

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